Random VP runs are the worst of the bunch IMO. VP runs are where you get more of the inexperienced toons that tend to get scared and/or frustrated and tend to bail on a group. But as others above have mentioned, its great for practicing stunning, thats if you make it that far.
I love doing Random CFO runs with smaller suits in the busy district. The only thing is most will not go unless there are 8 toons on the elevator. Teamwork is hit and miss in the cog round at best. When it comes time for the crane round, I just love hearing practically every toon say "May I operate the crane?". WoooHooo! Thats when I know it'll be a great run for practicing survival.
Its probably the best chance anyone will get to operate a crane when the floor is flooded with Red hat goons, because on random runs, this is the time all the toons go treasure hunting!